The journey between Bangalore and Tirupati and Tirupati to Bangalore is not that difficult to follow. First you need to reach the National highway 75 that is located in Krishna Reddy Industrial Estate. Once you are on National Highway 75, you will need to keep going till you reach Andhra Pradesh. Then take the Kanipakam Tirupati road till you reach National Highway 40. Then you need to follow National Highway 140 till you reach the Tirupati Bypass road. From there you need to keep going till you reach your destination. If you are taking a bangalore airport taxi, make sure that the driver knows this route.
Tirupati lies in the southern state of Andhra Pradesh which makes it a hot city. The temperatures in summer can soar upto 42 degrees C which makes it unbearable if you're not used to the heat. If you want to make the most of your trip to Tirupati then visiting during the months of September to March makes the most sense. September also marks the months of the festivities and this is why it is worth checking it out during this month.
There are three major routes that will take you from Bangalore to Tirupati. The fastest route is via National Highway 75 and National Highway 206. The other alternate routes are via the Anantapur Tirupati Highway and the National Highway 48.
The road conditions are excellent till you reach the Andhra Pradesh border. After that there are a number of speed breakers that you need to be aware of. There are also quite a few trucks that make driving a bit difficult. The road gets better again after Chittoor.