The journey from Wayanad to Calicut is via the National Highway 766. First you need to get to National Highway 766. Then you need to follow the highway till you reach your destination in Calicut.
A visit to Calicut during the winters is something that you should look forward to. This is because winter temperatures here are quite pleasant and it does not get very cold. The best time to visit Calicut and the best time to visit wayanad is pretty much the same. Winters are the peak season for tourists to come here so if you don't like it then you may want to avoid visiting Calicut during the winter. You may want to try coming here during summers. Summers do get hot and the temperatures can go up to 33 degree Celsius but if you are traveling by air conditioned cab then it will be easy for you to travel. Monsoons are not recommended to visit Calicut because it experiences heavy rainfall and it could be difficult for you to get from one place to another. However, if you have to visit Calicut during the monsoons then you can enjoy the harvest festival when you are here.
There is only one major route via National Highway 766 to reach Calicut from Wayanad.
The road conditions from Wayanad to Calicut are quite nice. You don't have to worry too much about it being a troublesome journey if you are traveling by Wayanad to Calicut outstation cabs. It is a short 3 hour drive and it will be comfortable and you will manage to enjoy yourself during the journey because of the beautiful view that surrounds you.